The Program
is aimed at:
- timely revealing, prophilactic medical examination and
prevention of complications of idiopathic dilated and hypertrophic
cardiomyopathies, including cases with family history of the
disease;
- prevention of viral myocarditis (VM), study of so called
“cardiotropic” and “hepatotropic” viruses and their mixed
infections (both separate and co-existing forms), and their effect
on VM formation and transformation into dilated cardiomyopathy;
- the use of modern tests and high technologies to study idiopathic
and secondary cardiomyopathies: hypertrophic, dilated and VM, their
diagnostic verification and evaluation of various spectrum of heart
insufficiency syndrom;
- prevention, differenciated approach to treatment, and
implementation of modern therapeutic approaches to mentioned above
pathologies and their complications (including heart insufficiency),
in specialized hospitals and outpatients clinics, throughout the
country, using continuous health care professional education and
post-graduate training;
- establishing contacts with leading cardiologic canters of the
world;
- working out of joint programs of knowledge and specialist
exchange;
- foundation of regular annual workshops and conferences, and of the
International Society of Cardiomyopathy;
- establishing strong ties with Cardiomyopathy Centers and
Associations from different countries through working out unified
research programs;
- evaluating the severity of the disease course and its prognosis
(including possible complications);
- special attention to be paid to distruction of the immune system
and degrading shifts, including low “immune-competency” of red
blood cells (changes in red-blood cell membranes on the background
of decrease in O2 transportation
- one of its main functions), at the expense of the increase of so
called spherocytous forms;
- revealing of microrheologic, morphofunctional and ζ-potential
disorders, and related microelement and vitamin metabolizm changes.
Special attention will be paid to symptoms relatively tipical for
brain diffuse changes – decrease in the restoration and adaptation
ability. Often, neurologic symptoms are already present in such
patients, before cardiologic ones are manifested (e.g. pronounced
symptoms of heart insufficiency), this fact indicates, that there is
strong relation between mentioned pathologies. We think, that local,
complete or incomplete demyelinization and hypodynamic or ischemic
disorders of brain and cardial afferent system together with
everything mentioned above contribute to progression of diffused
changes in brain (diffused atrophic changes in brain substance) and
manifestation of tipical neurologic symptoms. Cardiotropic and
hepatotropic virus combination leads to manifestation of
encephalopathy symptoms in rather short time (3-6 mnth), creating
diseased circle, where 40% of cases end in patient’s death.
Unfortunately symptomatic intervention at this stage gives only
slight and temporary improve in the general condition. On the
background of deeper and more serious changes occuring in the brain,
therapy used, has no positive effect on the regression of the
disease, and, what is more important, on the mortality prognosis,
thus is not able to distruct the diseased circle. If ignored, this
condition, we believe, causes serious pathologic changes in
transplanted heart (while no autoimmune incompatability is present)
some time after heart transplantation was performed. This may be the
result of the formation of the second diseased circle, that is
formed in the presence of immune system distraction and
degeneration, that already existed before heart transplantation.
This idea is reflected on the logo of our Society.
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