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Thrombolytic Therapy of acute Miocardial Infarction in Elderly Patients

N. Emukhvari,  E. Tsetskhladze
Tbilisi State Medical Universitety, Clinic  N1

181 Patients with first acute myocardial infarction were admitted to thrombolytic therapy with streptocinase. In group I age of 64 patients was 36-65 years, in group II of 69 patients was 66-75 years and in III group 25 patients exceeded 76 years (76-85 years). Rate of early angina and reinfarction was higher in groups I and II compared with group III.   Rate of acute heart failure among patients older than 76 years was higher, than in younger patients of groups I and II. 30 Day mortality among patients over 76 ears of age was higher in both groups especially in group I.
Literature:

        1.      Van de Werf F, Califf R. M. Armstrong P. W. on behalf of the GUSTO-1 Steering Commitee. Progress culminating from ten years of clinical trials on thrombolysis for acute myocardial infarction. // Eur Heart J, 1995; 16: 1024-1028.
2.      Lee K. L.  Woodlief L. H. et al. for the Gusto –I Investigators. Predictors of 30 day mortality in the era of reperfusion for acute myocardial infarction: results from international trial of  41 021 patients. // Circulation, 1995; 91. 1659-1668.
3.      Verheugt F. W. A. Meijer A. Lagrand W.  Reocclusion: the flip side of coronary thrombosis. // J Am Coll Cardiol, 1996; 27: 766-773
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